In cases of recurrent pregnancy loss, failed IVF attempts, or suspected intrauterine pathology, the possibility of chronic endometritis is carefully assessed.

Diagnosis is made using immunohistochemical staining with CD138 and CD56 markers.

For selected patients, treatment includes antibiotic therapy, intrauterine irrigation, and local therapies aimed at restoring endometrial health.

This approach is especially crucial for patients with implantation failure.

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